![]() The developers have made the graphics clear and full of small details. ![]() The game grabs your attention with simple yet polished 1-bit visuals. UD is a project that pays tribute to the classics of games of its genre, like Legend of Zelda, Gauntlet or Dragon Quest. The game is made by Josyan Team, previously involved in working on games like Tamiku, Zerotopian Invasion or Alex Kidd in MW remake. You’ll traverse the dungeons, fight enemies, acquire new, powerful items and solve puzzles. UnderDungeon it’s an astonishing and clever mix of classic RPG games with mechanics and levels from other genres. ![]() But along the way, you will meet allies and engage in a great adventure! Sounds easy? Nothing more wrong!Ī whole bunch of monsters to defeat, and secrets to discover. I enjoy the more outwardly ambitious titles too, but it’s refreshing to play a title that concentrates on a simpler approach.As a cute cat Kimuto, face the harsh world of work on your first day of the new job as a delivery guy. The stripped back, immediate response approach to gameplay is the antithesis of the epic, movie inspired blockbusters that dominate the gaming landscape. Most of the time I found myself delaying the correct action in order to see every possible response, almost the complete opposite of how most games are meant to be played. There are a vast amount of individual actions to perform and an accompanying range of reactions. Some screens contain hints in the background whilst others simply need you to work your way through the options. Every screen has a number of interactive objects or characters and to progress you need to puzzle out the order in which to prod, poke, push, lick, jump on them. Unlike many other games, where discussion of the mechanics and controls can occupy several paragraphs of insightful commentary, here the controls are delightfully simple as you click away with your mouse. With all this being said, one of the most interesting things about Chuchel is how difficult it is to summarise in written form. If your main criteria for a game’s value is its length, though, Chuchel is not for you. Whilst this sounds slight, the ratio of fun to gameplay time is much more impressive, and I’d certainly choose Chuchel over many more substantial games. Completing the game and getting the achievements is possible in just a couple of hours. The only negative is that it is clearly a very short experience. Almost every one of the game’s 30 screens contains numerous opportunities for experimentation and offers the potential for a range of cute and funny animations. It should be clear that I loved Chuchel and found myself smiling far more than is natural for such a jaded and cynical old man. The result is a true feeling of playful exploration, where each click is generally rewarded by a suitable animation, whether successful or not. Interactive objects are generally easy to spot but don’t feel shoehorned into the scenes either. This unity of vision is one of the most impressive parts of the game, and perfectly complements the gameplay. All of the weird and bizarre creations feel like they belong and, as with Samorost, Machinarium and Botanicula before it, the overall effect is of an impressively cohesive and well designed world. Utilising the full spectrum of bright colours and exhibiting a lovely crude hand-drawn aesthetic, the inhabitants of Chuchel are all chock-full of character. The most obvious place to start with Chuchel is with its vivid artstyle. ![]() Full of grotesque and cute characters and buttons, levers and objects to push, pull, and manipulate, Chuchel’s quest for a tasty cherry has more imagination in each screen than many big budget games demonstrate in their entirety. Instead of the weird sci-fi stylings of Samorost, however, Chuchel takes place in a colourful world that looks and feels like a kid’s cartoon. Coming from the makers of the wonderfully imaginative Samorost games, Chuchel continues the static screen environmental puzzling of its predecessors. ![]()
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![]() ![]() Discover Christian Scott's Biography, Age, Height, Physical Stats, Dating/Affairs, Family and career updates. On a separate student stage tucked in near the Fifth on Teeling front door flautist Sarah Chaplin was among the jammers to make a strong impression as summer school participants took to the stand adding to the lively atmosphere until well into the wee small hours.Christian Scott was born on 31 March, 1983 in New Orleans, LA, is an American jazz composer and trumpeter. Hamilton was joined by the great jazz writer Mingus biographer Brian Priestley on keyboards, Mike Nielsen, guitar, Matthew Halpin and Cathal Roche, saxophones, Damian Evans, bass, and Steve Davis, drums. Later at Sligo music venue Fifth on Teeling ( pictured) tutors and students performed and jammed on two stages, the North and South Irish Jazz Allstars led by Belfast trumpeter Linley Hamilton who had earlier emceed at the Hawk’s Well, the main draw. Scott’s garrulous band intros, at least five minutes long for each musician, were far too much but apart from this it was an engrossing set, protest song ‘Ku Klux Police Department’, commenting on police brutality, the highlight. Bassist Kris Funn was a busy presence throughout and needed to be as the tension was ratcheted up. Scott has real personality when he plays, displaying strong involving soloing momentum, his tunes blessed with a strong melodic anthemic sense channelling Milesian jazz-rock and scintillating meta-funk rhythms referencing Scott’s New Orleans roots. The couple married last year and held hands at one point on stage. Corey Fonville (in the photo, just visible to the right of Scott) was a strong and active polyrhythmic presence on drums laying back a little on the featured vocal spots when the band were joined by Scott’s wife singer Isadora Mendez Scott. Her style recalled a young Bobbi Humphrey. The front line was Scott, alto saxophonist Braxton Cook, tart and tough when needed, and the very impressive 19-year-old flautist/vocalist Elena Pinderhughes new in the band this past week, a presidential scholar at the Manhattan School of Music. Pianist Lawrence Fields' style was characterised by strongly rhythmic quartal harmony all night on the Steinway before switching to Fender Rhodes for the encore. Scott, sporting a smart snood-type scarf, was unabashed, exuberant as he dug into bravura solo breaks playing his customised Dizzy-like trumpet with its horn set at a rakish angle. The young actor drew on the tenderness and passion of Milligan in his performance, the Goon’s words interspersed with clips of music by Bill Evans, Django Reinhardt, and Ornette Coleman.Īt the Hawk’s Well theatre later in the evening the Christian Scott aTunde Adjuah band was delayed as the airline had lost some of the band’s luggage, so the band ending up taking to the stage an hour late, the set not quite as planned with missing instruments a factor. Yeats paintings, and earlier at lunchtime in St Edward’s school where the Sligo Jazz Project’s summer school has been taking place, actor Barry Cullen performed a monologue based on interviews the great comedian and writer Spike Milligan, who had deep Sligo roots, granted to a number of writers, airing Spike’s thoughts about jazz and the music's extraordinary effect on him. In an added extra at the Sligo Jazz Festival this year in the atrium of the Model, the arts centre home to the extraordinary Niland collection of Jack B. ![]() ![]() ![]() He lived together with his wife for 5 years before getting married.Simon was raised in a Catholic household but is now an agnostic.Source – Simon Baker in Paris at the French Premiere of I Give it a Year in April 2013 (Georges Biard / Wikimedia / CC BY-SA 3.0) Simon Baker Facts To keep fit, he surfs, plays water polo, and eats loads of fish, rice, and salad. Simon Baker made his TV show debut as Constable Sam Farrell on the 1992 TV show E Street. In January 2021, it was revealed that the couple had separated in April 2020. Rebecca Rigg (1998–2020) – Simon and Rebecca got married on October 2, 1998, and have 3 children together – a daughter named Stella (born in 1993) and 2 sons named Claude (born in 1998), and Harry (born in 2001).Patricola Public Relations (Publicist), Beverly Hills, California, USAħ4 kg or 163 lbs Simon Baker in an Instagram Selfie in July 2014 (Simon Baker / Instagram) Girlfriend / Spouse.Creative Artists Agency (CAA) (Talent Agent), Los Angeles, California, USA. ![]()
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Use a heat gun, if you do not have access to a heat gun you may use a strong hair dryer.Add additional weight to areas that are needed, until the desire results are achieved.Leave the item in its original plastic bag sealed, on a sunny day ideally 70+ degrees temperatures on a flat surface for at least 30 Min.If the item is out of shape, it will return to its original shape by following these steps: This product is made of Polyurethane or Urethane and is intended to be more flexible than fiberglass. ![]() We Will Not Reimburse Painting/Prep Work or Installation Fees.Please Note It Is You and Your Body Shop’s Responsibility to Test Fit the Parts Prior to Prep, Paint, and Installation.Contact Us Immediately If There Is Any Fitment Issues or Appears To Be Damaged.Test Fit All Parts Prior to Prepping, Paint and Final Installation. ![]() ![]() ![]() The ongoing service game, Fallout 76, could also point us to some clues about Fallout 5, as past entries have routinely hinted at the future ones. Speaking with IGN, Todd Howard has confirmed that Fallout 5 will be Bethesda Game Studios’ next game after The Elder Scrolls 6 which itself will follow on from Starfield releasing in 2023. In the past, places like Florida and New York have been rumoured for future entries, but they could just as easily switch it up. This means aspects like the overall story, location, and themes have all been roughly drafted out by this point, along with any key gameplay mechanics and ideas they'll want to implement.Ĭonsidering Bethesda like to focus on east coast America in their titles, we'd imagine they'll set the next one there too. The creation of Fallout 5 has been confirmed, albeit at this time it merely implies that work is being done on the game. Alongside announcing that Fallout 76 has seen 15 million players enter its wasteland, Bethesda has revealed the games next. It takes place in the year 2297, ten years after Fallout 4, and two. Animal studies have consistently confirmed radiation induction of thyroid. By Smangaliso Simelane Published Fallout 5 is yet another instance of Bethesda announcing its upcoming games too early, and this may be more harmful than helpful for building hype. Story-wise, we know nothing about the next Fallout, but Bethesda sure do, as Todd Howard confirmed the studio has a one-pager on the title. As with past Fallout games, Fallout 5 takes place in a post-nuclear apocalypse setting. Medullary thyroid carcinomas28,29 account for 5 of malignant thyroid nodules. However, if there's one thing we'd bet our reputation on, it's that Fallout 5 will feature the largest map of any first-person Fallout game yet. Due to how far in the future it's expected to come out though, it's hard to say what video game evolutions it could take advantage of in terms of gameplay. It's safe to say any future Fallout game will retain the first-person perspective and open-world of the last few titles, as the series abandoned its roots as an isometric game long ago. ![]() ![]() ![]() Iggy and Spike explain to the brothers the purpose of the meteorite piece they are after, and they come to an agreement with Mario and Luigi to return Daisy to them, in exchange for the meteorite piece. Despite their forwarded intelligence, they manage to crash the vehicle and are captured and tied to one another by Mario and Luigi. Iggy and Spike, now of higher intelligence, return to Koopahari Desert driving a six-wheeled vehicle. Iggy strapped to the Devo Chamber to "Advance" his intelligence Like Spike, Iggy is strapped to the Devo Chamber machine next and his intelligence is advanced. Iggy is confused when Spike re-emerges from the Devo Chamber reciting mathematical equations. In reality, Koopa plans to advance his intelligence with the Devo Chamber, under the notion that they will cease to make senseless mistakes after. Iggy mocks him, believing that Spike is going to be de-evolved to a Goomba. Koopa becomes enraged at their decision to return to him instead of capturing the brothers, and straps Spike to the Devo Chamber. They later spot Mario and Luigi from afar in the Koopahari Desert, and return to Koopa's Tower to inform Koopa. He sends them back out to find Mario and Luigi. Iggy and Spike deliver Daisy to Koopa, who becomes enraged that they did not successfully retrieve the meteorite piece. Luigi reaches out for Daisy as she's being dragged into the Dinohattan portal, snatching the meteorite necklace off her. They take hold of Daisy, dragging her through the tunnels chased by Mario and Luigi. They initially kidnap Daniella after she is dropped off by Mario at her apartment, though they later come to find Daisy in the New York sewers with Mario and Luigi. Iggy and Spike are introduced in Brooklyn, New York, scouting for women to kidnap that may be Daisy. Iggy (left) and Spike (right) scouting for Daisy in Brooklyn After their intelligence is raised, they slowly begin to realize they despise how Koopa treats them, and eventually betray him and ally with the protagonists. At some point during the movie, Koopa grows tired of their low intelligence, and reasons he can advance their intelligence with his Devo Chamber machine. They frequently bicker and abuse each other. Iggy claims to be the "brains" of the duo, though they are shown to think alike, forming schemes together and finishing each other's sentences on occasion. Iggy and Spike are initially depicted as incompetent low intelligence minions of their cousin, Koopa, and serve as an antagonist duo for a majority of the movie. His namesake is based on the Super Mario franchise Koopaling Iggy Koopa, though their only similarity is that they are both high-ranking minions to Koopa ( Bowser in the video games). The change has been welcomed by many as a common sense decision to avoid perpetuating harmful stereotypes.Iggy (later referred to as Ignatius by Spike ) is the cousin and henchmen of President Koopa in the 1993 Super Mario Bros. Nintendo's official Twitter account noted the name change in late April but did not specify the reason behind it. Gaming news website Polygon has praised Nintendo's decision to change the character's name, noting that "'Blackie' is an incredibly unfortunate name - for so many reasons." The website also expressed mock concern that some may object to the change as an example of cancel culture.Ĭulture website Bounding into Comics has also commented on the name change, suggesting that it was likely not meant to cause offense when the character was created in the 1980s. franchise, including Foreman Spike, voiced by Sebastian Maniscalco. The film includes references to obscure aspects of the Mario Bros. Movie," which has broken box office records for video game adaptations and animated films. The name change has been implemented not only in the video game but also in "The Super Mario Bros. It is speculated that the character's original name, "Blackie," was meant to reference his black beard or perhaps "Brakey" or "Breaky," fitting for a demolition worker. The name change comes after Western audiences pointed out that "Blackie" translates to a racial slur for Black people.Īccording to Fox News, the character, Foreman Spike, is depicted as a muscular, white construction worker with black facial hair. Nintendo, the Japanese video game company, has announced that a character named "Blackie" in its 1984 video game "Wrecking Crew" has been officially renamed "Spike" for all audiences. ![]() ![]() ![]() The dentist is, of course, Italian and spends most of his time muttering on about everyone thinking Italians are just the Mafia and nothing else. However Columbo does go to the dentist - something that's always worth seeing. There's so much going on in this episode that man there's barely any time for a sub-plot. And in America you need to be rich to be elected - I'm sure we all await the day with baited breath when the US President is someone who spent most of their lives in the slums trying to get out, although the chances of that ever happening seem rather slim. Now you know this is going to rank high when a politician is involved - it must be one of the smuggest professions on the planet after all. It's only as the end nears and he's getting increasingly desperate that the frustration really shows. However being a good politician, Hayward does a very good politician act of covering it up and being diplomatic - okay he's no Tony Blair at it but you get the idea. ![]() Here you have a politician who doesn't think his fake story of death threats and murder is being believed! Which of course it isn't because the story is as likely as anyone claiming Cher has never had plastic surgery. And boy does this take a lot.Įxtra points have to go for the fact that the murder happens whilst the murderer is supposed to be under police protection, although the way Hayward actually manages to allude them doesn't exactly inspire police confidence! How annoyed does the murderer get with Columbo? You can usually tell how good a Columbo episode is going to be, on the basis of how much effort it takes to get the person killed in the first place. Columbo had removed it three hours before. Unfortunately for him, Columbo has him big style. Playing up to the fact that the police think he's faking everything, he points at the bullet hole and asks them if they still think he's faking it! Match the bullet in the wall with that that killed Stone and what's the betting it's from the same gun? Well? Hours later on he uses a firecracker to make it look like he's just been shot. Before going off to cast his vote, Hayward shoots through the window from the hotel balcony, and smuggles the gun out again. It's back at the hotel on election day that he gets his evidence.ĭespite the hotel suite supposedly being a secure area, Hayward has smuggled in a gun with a silencer. The only one is at a petrol station which was closed as they ran out of fuel! And they had to have followed the car rather than wait, because who knew anyway was driving to the beachhouse?Īnd why did Hayward order a new jacket identical to the one that Stone died in?Ĭonvinced that the whole death threats are false, he goes around trying to find out how and is nudged on by the fact that there's no phone near the beachhouse where anyone could have made the phone call to the police. The murderer could have driven in behind Stone and used his headlights, however then the angle of the shot would have been wrong. The murder happened in pitch black for starters as the street light was broken. Stone's clothing is tough and reliable but the watch found on him was cheap and shoddy. The fun for Columbo begins very early on because ultimately little about the murder makes sense. Cleverness of the way Columbo catches out the murderer Later he phones the police, and proclaims that the non-existent gang who issue death threats, have actually carried one out.Ĭolumbo is at the dentist when he hears the news. He then rushes home for a surprise birthday party for his wife. Once dead he replaces Stone's watch with a new one, changes the time and smashes it. On his arrival he flips on the lights and kills him. In reality he drives off to the beach house too, and waits for Stone there in the garage way. ![]() Swapping jackets, he tells Stone to drive off to Hayward's beach house knowing the police will follow. Hayward tells Stone he's going to break it off with Linda in person but he needs cover. Not impressed, Hayward concocts a plan to get Stone - a man whom he has come to hate - out of the way for good, and make the threats on his life look more real.įrom his hotel suite, he sends his police guard to the lobby for some cigars. ![]() Happily married is the only way he's going to be. Stone insists that Hayward breaks off his clandestine relationship with Linda Johnson who works as secretary to Hayward's wife. In order to help, his Campaign Manager Harry Stone has arranged a plan to boost the votes - a phoney series of threats on Hayward's life, convincing enough to ensure Hayward gets a huge amount of police protection and, of course, lots and lots of publicity. “This Columbo episode proves, politicians are just as likely to be evil murdering scum as anyone“Įlection day is rapidly approaching and Senate candidate Nelson Hayward is only too aware that it's going to be a tight battle against his opponent. ![]() ![]() ![]() 100 free, secure and easy to use Convertio advanced online tool that solving any problems with any files. When everything is completed, make sure to check your PDF with a screen reader or the built-in “Read Out Loud” option. Best way to convert your PPS to PPT file in seconds. ![]() To change that order, you can drag and drop the tags in the “Order” panel. Each tag on a slide is numbered in the order that it will be read in. Once everything on the slide is tagged correctly, check that the reading order matches the visual flow of the slide. You can set the alt-text by right-clicking on the image or using “Tools”/”Accessibility”/”Set Alternate Text.” If it had alt text in PowerPoint that text should have transferred over, but a manual check is always a good idea. If an image does convey meaning, make sure that it has alternate text defined. This will cause that image or text to be ignored by a screen reader. If something is purely decorative or does not convey meaningful information (such as header text that is identical on every slide), choose the “Background” option. For example, for body text on the slide, choose the “Text” option. Once you have it selected, choose the option in the “Touch Up Reading Order” panel that corresponds with the structure you’ve selected. Click and drag to select the text or image you want to tag. Usually the conversion process does tag items, but manual editing is necessary to make sure it’s done correctly. ![]() Under the “Accessibility” Tools option, use the “Touch Up Reading Order” tool. Once you have saved the file as a PDF, open it in Adobe Acrobat. Watch Acrobat automatically convert your file from PDF to PPT. Select the PDF file you want to turn into a PPTX file. To start with, make sure that the presentation file is fully accessible – all images that convey meaning need to have alt-text, for example. Online Tools Convert PDF to PowerPoint How to convert PDF to PPT Follow these easy steps to convert a PDF into a Microsoft PowerPoint presentation: Click the Select a file button above, or drag and drop files into the PDF drop zone. When converting a PowerPoint file to Portable Document Format (PDF), “Save as PDF” is just the first step. From the desk of Lyssa Rowan, B.A., Web Developer ![]() ![]() ![]() Photo: Michael Burnett, Ho-Ho plant, S.U.A.S contest, Houston, TX 1987 Grant Brittain, f/s hand out, Vancouver, B.C. Photo: Eric Nash, invert, Whittier Skatepark, Whittier, CA Photo: Hagop Najarian, Go Skate contest, Sacto, CA 1985 Lien air, Kona, Jacksonville, FL: photo: Chuck Hultsįastplant, Skate Ranch, Vancouver, BC photo: OĪndrecht, Mountain Manor Ramp, Alhambra, CA Photo: Mofo., b/s air, 24th & Mission BART station. Photo: Mofo, f/s 5-0 Terror in Tahoe Contest, Lake Tahoe, CA 1985 Grant Brittain, f/s nose pivot, Vancouver, B.C. Photos: Hagop Najarian, Tuck-knee f/s air and lien air, Mountain Manor, Alhambra, CA f/s ollie, Sadlands, Anaheim, CA Photo: Miki Vuckovich, b/s ollie, Sadlands, Anaheim, CA Photo: Greg Baller, sadplant, Border Wars contest, Vancouver, B.C. Photo: O, bean plant to tail, Neil's backyard ramp The Heated Wheel "Boost" hand painted decks Hand painted Larry Bertleman, Lance's tile art is below. The Heated Wheel "Coffee Break" hand-painted numbered run of only 50. Neil's last pro model to date.ĪWS Duane Pitre from the "Notebook" series The Heated Wheel "Squirrel" linoleum print deck, 2006. According to Neil only around 100 were made. G&S "Rocking Dog 1" pre-dates the later Picasso-esque version with the man holding the dog. "Am I The Guy You've Been Trying To Draw?"Īlternate cover art for Dinosaur jr.'s Greatest Hits album An earlier version of this drawing was used for a G&S sticker. I got the "Squirrel" lino print on wood in Dino jr. "Traffic Games" acrylic on denim fabric, photo: Neil Blender "Volvo" with my cat Daisy checking it out. "Worm Trainer" acrylic on denim fabric, photo: Neil Blender ***This is going to be an ongoing post with updates any time I find new material by Neil. Nobody skates or creates art like him, a total original. There's not always stuff up there but it's worth the wait. The Heated Wheel is still around but you can only get it from Neil on eBay. These days Neil sells his stuff through eBay ever since he shut down his The Heated Wheel site. Just make sure to get one made in Japan, not Taiwan, way better quality. If you know anything about guitars, you'll know that these sound about as good as a vintage Martin at a fraction of the cost. One of my favorites, "Traffic Games", I got when I traded Neil a very rare 1970 Yahama 12-string acoustic. ![]() (see clip near the bottom of this post) I think I have about 10 of Neil's paintings and prints now, not nearly enough I think. Neil was even the reason that I begged my parents to let me build a mini ramp in our backyard after I saw his footage in Santa Cruz Speed Wheels "Speed Freaks". These days I'm riding a Small Beating deck made by the PS Stix woodshop a/k/a Schmitt Stix. G&S wood just wasn't up to snuff with the John Lucero Schmitt Stix deck I had before it so I pretty much stuck with Schmitt Stix/New Deal after that. I only had one Blender deck when I was a kid, the "Coffee Break" one of course circa 1987. The ad was for a mail order skate shop and his graphics immediately stood out from all the skulls, 80's neon art damage, monsters, etc. The ad was in the August issue of Transworld. It was the Picasso-influenced "Rocking Dog" board. Back in the summer of 1986 just as I was turning 12 I saw Neil's artwork for the first time. I felt personally offended that someone would take something that's such a fond memory for me and completely ruin it for the sake of greed. After that whole debacle with the lame messenger bag company using Neil's famous "Coffee Break" graphic for their $400 bags I felt like a part of my childhood got raped. Here it is, "The Loaf" meaning Blender by the barrel-full, an all-you-can-eat buffet of tastiness. This is probably going to be the biggest post I'm ever going do but when I started gathering material for this it just kind of snowballed. OK, "art week" here on the site wouldn't be complete with something on my main man Neil. ![]() ![]() ![]() And Salmonella ingestion can result in diarrhea, fever, stomach cramps, and other symptoms.Ĭoxiella burnetii, bacteria that cause Q fever.Ī study published yesterday in Emerging Infectious Diseases finds low a incidence of pathogens with bioterrorism potential in the Netherlands, which the authors say would hamper efforts to isolate them from natural sources for intentional release.Ī team led by Amsterdam University researchers used data on diseases published from 2009 to 2019 to calculate the average annual incidence of pathogens considered high risk by the European Medicines Agency or the US Centers for Disease Control and Prevention. They said Aspergillus can trigger allergic reactions or infections, especially in people who have underlying health conditions. The ADHS urged consumers who have products from the affected batch numbers to dispose of them. The one that yielded Aspergillus was plant trim, a product called Cherry Punch. ![]() Three samples that were positive for Salmonella-Cap's Frozen Lemon, Twisted Lemonz, and Ghost Train Haze-involved live resin concentrate. ![]() The four recalled products are all from the same cultivator, the Cannabist. The Arizona Department of Health Services (ADHS) said no illnesses have been reported and that its warning comes after its lab auditors found false-negatives for contaminants that were reported from a licensed marijuana laboratory. ![]() Arizona is one of 23 states that has legalized marijuana for recreational use. Several Arizona marijuana establishments have voluntarily recalled certain products over potential contamination with Aspergillus and Salmonella. Only 56 safety outcomes were seen in the study, and the overall rate of outcomes among COVID-19 vaccinees who received SV was not statistically significantly different than among those who did not receive SV (6.5 vs. The authors used surveillance data from December 11, 2020, to May 21, 2022.ĭuring the study period SV was uncommon, used by just 0.7% of 8,455,037 people for dose one and 0.3% of 7,787,013 people for dose two. In the second study, safety data on simultaneous vaccination (SV) with primary-series mRNA COVID-19 vaccines was evaluated, based on reports in the Vaccine Safety Datalink. elderly population, no statistically significant increase in risk was identified for ITP, DIC, and Myo/Peri following COVID-19 mRNA vaccination for primary series and monovalent boosters, " the authors concluded. " Of six AEs evaluated in two independent population-based studies including the U.S. The risk for AMI was reduced to nil after adjusting for other factors. For the Moderna vaccine, the rate ratios were 1.01 (95% CI 0.82 to 1.26) for the primary series and 1.05 (95% CI 0.998 to 1.11) for the booster. A subsequent study on booster doses included 6,156,100 people who received one monovalent (single-strain) booster dose.Īdjusted incidence rate ratios (IRRs) were calculated for these serious heart and circulatory conditions, among other adverse events (AEs): acute myocardial infarction (AMI), myocarditis/pericarditis (Myo/Peri), immune thrombocytopenia (ITP), and disseminated intravascular coagulation (DIC).įor the Pfizer-BioNTech primary series and booster, the AMI IRR was 1.04 (95% confidence interval 0.91 to 1.18) and 1.06 (95% CI 1.003 to 1.12), respectively. The first study, which looked at self-reported safety events for those 65 and older, included 3,360,981 people who received 6,388,542 primary mRNA series doses. Two new studies show COVID-19 vaccines are safe in older adults and when administered simultaneously with non-COVID vaccines. ![]() |
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